介孔分子筛MCM-41固载席夫碱与醋酸锌共催化“一锅法”合成噻唑啉酮衍生物

A new simple and efficient one-pot synthesis of thiazolidinone derivatives via aldehydes, amines and mercaptoacetic acid in the presence of Zn(AcO)2-Schiff base complex immobilized on MCM-41 is described. A variety of aldehydes and amines were engaged in the study and afforded respective thiazolidinones in high yield (up to 98%). Moreover, consistent activity of recovered catalyst was found to be almost same up to five cycles in 80% yield.