Correlation between stroke types, lesion location and degree under the background of aging

Objective: To explore the correlation between stroke types, lesion location and degree under the background of aging. Methods: 10ml venous blood samples were taken from all subjects at the time of admission, the third day and the seventh day after onset, and the levels of serum homocysteine (Hcy), whole blood C- reactive protein (CRP) and other biochemical indexes were detected. Serum S100β concentration was determined by immunochromatography, and PARK7 content was determined by ELISA. Results: The occurrence of stroke events was closely related to the degree of blood glucose, total cholesterol, low density lipoprotein, homocysteine, C-reactive protein and triglyceride, but not to the degree of high-density lipoprotein. The neurological deficit score in CI group showed that the more serious the disease was, the higher the plasma Hcy concentration was. There was no significant correlation between age and NHISS score. Conclusion: Plasma Hcy level in patients with acute stroke reflects the severity of their illness, which is helpful to evaluate prognosis and guide clinical treatment.