Analysis of the Epidemiology and antibiotics resistance of acinetobacter baumannii

OBJECTIVE To monitor and explore the epidemic situation in our hospital,so as to provide antibiotics resistance of the clinical isolates of Acinetobacter baumannii(ABA),and to guide the rational application of antibiotics in clinic.METHODS ABA isolated from clinic from 2007-2010 were retrospectively analyzed.The specimen source and infection in different departments and drug resistance were also analyzed.RESULTS The detection rate of ABA was increasing quickly.Most of them were isolated from sputum samples(71.29%).ABA were obtained mainly form ICU word(33.33%),neurosurgery ward(19.02%)and respiratory ward(10.84%).ABA showed high drug resistance and multi-drug resistance.IR-AB(imipenem-resistant ABA)infection was found mostly in ICU,accounted for 43.82%,and followed by the neurosurgery word 19.48%.Polymyxin showed the lowest drug resistant rate to Acinetobacter baumannii was 16.67%,followed by tocefoperazone\sullbactam(43.10%),minocycline with 44.44%.CONCLUSION The drug resistance to ABA is very serious.It is important to select proper antibiotics according to the results of antibiotics susceptibility tests and epidemic characteristics,and sterilization and isolation should be paid attention to and prevalence of most-drug resisant isolates should be controlled.