Carboxy-terminal fragment of fibroblast growth factor 23 induces heart hypertrophy in sickle cell disease.
2017
Cardiac remodeling is frequently observed in patients with sickle cell disease (SCD), and contributes to cardiac dysfunction and premature death.[1][1],[2][2] Cardiac dysfunction in SCD has been related to chronic anemia and low oxygen saturation. However, the mechanisms whereby they induce cardiac
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