Chromosome mapping in domestic pigs (Sus scrofa): MPI and NP located to chromosome 7

Four fusions between mouse myeloma cells and swine splenocytes have been produced, resulting in 19 mouse x swine hybrid cell lines. A study of the occurrence of 7 enzymes of swine origin in the 19 hybrid cell lines has been carried out. The 19 cell lines were karyotyped. They contained the original mouse chromosomes but only few swine chromosomes. The swine enzymes NP and MPI always occurred together in the same hybrid lines and their occurrence was consistent with the presence of swine chromosome no. 7. It was therefore concluded that NP and MP are syntenic and located to swine chromosome 7.