Experimental Candidosis in Animals and Chemotherapy

Members of the genus Candida are widely spread. They are present as endosaprophytes in the gastrointestinal tract of man and the majority of animals or as exosaprophytes in the environment. Various Candida spp. may be responsible for pathological manifestations, but Candida albicans is considered to be the species with the highest potency for morbidity and mortality, mainly in immunocompromised individuals or when predisposing, known or unknown, factors or regimens are present. Any organ may be infected, but superficial infections constitute by far the highest incidence.