Acute inhalation of hypertonic saline does not improve mucociliary clearance in all children with cystic fibrosis

Background Little is known of how mucociliary clearance (MCC) in children with cystic fibrosis (CF) and normal pulmonary function compares with healthy adults, or how an acute inhalation of 7% hypertonic saline (HS) aerosol affects MCC in these same children.