Human Pluripotent Stem Cell-Derived Hepatocytes Show Higher Transcriptional Correlation with Adult Liver Tissue than with Fetal Liver Tissue

Nidal Ghosheh,Barbara Küppers-Munther,Annika Asplund,Christian X. Andersson,Petter Björquist,Tommy B. Andersson,Helena Carén,Stina Simonsson,Peter Sartipy,Jane Synnergren

Human Pluripotent Stem Cell-Derived Hepatocytes Show Higher Transcriptional Correlation with Adult Liver Tissue than with Fetal Liver Tissue

2020

Nidal Ghosheh
Barbara Küppers-Munther
Annika Asplund
Christian X. Andersson
Petter Björquist
Tommy B. Andersson
Helena Carén
Stina Simonsson
Peter Sartipy
Jane Synnergren

Human pluripotent stem cell-derived hepatocytes (hPSC-HEP) display many properties of mature hepatocytes, including expression of important genes of the drug metabolizing machinery, glycogen storag...

Keywords:

Induced pluripotent stem cell
Cell biology
Gene
Biology
Fetus
liver tissue
Glycogen
Cell and molecular biology
adult liver

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