Radiation Damage to Skin-Fundamental and Practical Aspects .Edited by H.JAMMET, F.
1987
. The carcinogenic effects reported include those resulting from UV, beta-ray and X-ray exposures. Combined injuries, burns, trauma, as these interact with whole body radiation are detailed from experiments on animals with some recommendations on therapy for humans which might occur in some accidents . IV. A section devoted to physical and biological dosimetry covers data from several accidents and correlates the doses with the outcome from these biophysical methods of dose assessment . These indirect methods of dose assessment are detailed for hand exposures using measurements of capillary loops in the nailbed for instance, and thermal methods of injury monitoring for biological dose evaluation . Cytological and biochemical methods, as well as chromosomal analysis of hair matrix cells, as biological dosimeters are discussed pointing out the sensitivity of these methods . Twoin vitro methods of fibroblast measurement are presented to evaluate dermal effects . V. In the section on high- dose radiation-induced lesions both light and electron-microscopic effects are detailed for epidermis, dermis and muscle. This is followed by a discussion of biochemical and immunochemical response of thesetissues. VI. In the section on clinical management of cutaneous and subcutaneous lesions the stepwise medical and surgical management is discussed from the experience from planned laboratory exposures and from the clinical experience gained from accidental radiation injury cases . VII. A section on current radiation
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