ªí—''àââ'◊ŸÉ ∑'â—Ÿà Factors Affecting the Blood Concentration of Cyclosporine in Renal Transplant Patients

Abstract Determining factors affecting the blood concentration of Cyclosporine by multivariate analysis found that thefactors that correlated with blood concentration of cyclosporine were hematocrit (Hct, %), albumin (Albumin (Alb,g/dL), SGOT (IU/L), cholesterol (Chol, mg/dL), cyclosporine dose (Dose, mg/kg), and interaction of SGOT andalbumin. This can expressed as: 1 O“®“√¬a, §≥–‡? —™»“ μ√ a iA“« ‘∑¬“≈ —¬iA“ “√§“i O”‡?O° —π∑√™ —¬ ® —sA« —¥iA“ “√§“i 44150, 2 √Os»“ μ√“®“√¬a, 3 √Os»“ μ√“®“√¬a, 4 O“®“√¬a, §≥–‡? —™»“ μ√ a iA“« ‘∑¬“≈ —¬¢Oπ·° aπ O”‡?O‡i ◊Os ® —sA« —¥¢Oπ·° aπ 40002 1 Lecturer, Faculty of Pharmacy, Mahasarakham University, Kantharawichai District, Maha Sarakham 44150, Thailand. 2 Assoc. Prof., 3 Assoc. Prof., 4 Lecturer, Faculty of Pharmaceutical Science, Khon Kaen University, Mueang District, Khon Kaen 40002,Thailand.* Corresponding author: Rodchares Hanrinth, Faculty of Pharmacy, Mahasarakham University, Kantharawichai District, Maha Sarakham44150, Thailand. Received: 27 April 2008; Accepted: 25 June 2008.