Effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin.

Marleen Depré,A. Van Hecken,M. Oeyen,I. De Lepeleire,Tine Laethem,Paul Rothenberg,Kevin J. Petty,Anup Majumdar,Tami Crumley,Deborah Panebianco,Arthur J. Bergman,Jn de Hoon

Effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin.

2005

Marleen Depré
A. Van Hecken
M. Oeyen
I. De Lepeleire
Tine Laethem
Paul Rothenberg
Kevin J. Petty
Anup Majumdar
Tami Crumley
Deborah Panebianco
Arthur J. Bergman
Jn de Hoon

Objective To examine the effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin. Aprepitant is a neurokinin-1 (NK1)-receptor antagonist developed as an antiemetic for chemotherapy-induced nausea and vomiting.

Keywords:

Drug interaction
Medicine
Anesthesia
Aprepitant
Pharmacodynamics
Antiemetic
Pharmacology
Warfarin
Vomiting
Nausea
Pharmacokinetics

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