Home-based pre-surgical psychological intervention for knee osteoarthritis (HAPPiKNEES): a feasibility randomized controlled trial

Objective:To determine the feasibility of conducting a trial of a pre-surgical psychological intervention on pain, function, and mood in people with knee osteoarthritis listed for total knee arthroplasty.Design:Multi-centre, mixed-methods feasibility randomized controlled trial of intervention plus usual care versus usual care.Setting:Participants’ homes or hospital.Participants:Patients with knee osteoarthritis listed for total knee arthroplasty and score >7 on either subscales of Hospital Anxiety and Depression Scale.Intervention:Up-to 10 sessions of psychological intervention (based on cognitive behavioural therapy).Main measures:Feasibility outcomes (recruitment and retention rates, acceptability of trial procedures and intervention, completion of outcome measures), and standardized questionnaires assessing pain, function, and mood at baseline, and four and six months post-randomisation.Results:Of 222 people screened, 81 did not meet inclusion criteria, 64 did not wish to participate, 26 were excluded...