Diphtheria toxoid nanoparticles improve learning and memory impairment in animal model of Alzheimer’s disease

Samane Heydari,Mojtaba Hedayati Ch,Farshid Saadat,Mahmood Abedinzade,Iraj Nikokar,Ehsan Aboutaleb,Abolfazl Khafri,Ali Rezaei Mokarram

Diphtheria toxoid nanoparticles improve learning and memory impairment in animal model of Alzheimer’s disease

2019

Samane Heydari
Mojtaba Hedayati Ch
Farshid Saadat
Mahmood Abedinzade
Iraj Nikokar
Ehsan Aboutaleb
Abolfazl Khafri
Ali Rezaei Mokarram

Background Alzheimer’s disease (AD) is a neurodegenerative disorder involving memory. The present study aimed at evaluating the effects of encapsulated diphtheria toxoid (DT) on behavioral learning impairment, and XBP1 mRNA splicing in AD.

Keywords:

Disease
Alzheimer's disease
Diphtheria toxin
XBP1 mRNA splicing
Immunology
behavioral learning
Diabetes mellitus
Endocrinology
Medicine
Animal model
Internal medicine
memory impairment

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