Enantioselective synthesis of indolizidine (−) 237A [(3R,5S,8aR)-3-butyl-5-(1-oxopropyl)-octahydroindolizine]

Giang Vo Thanh,Jean-Pierre Celerier,G. Lhommet

Enantioselective synthesis of indolizidine (−) 237A [(3R,5S,8aR)-3-butyl-5-(1-oxopropyl)-octahydroindolizine]

1999

Giang Vo Thanh
Jean-Pierre Celerier
G. Lhommet

Abstract A highly enantioselective synthesis of the indolizidine alkaloid (−) 237A is described via the diastereoselective reduction of a heterocyclic enamine.

Keywords:

Alkaloid
Enantioselective synthesis
Organic chemistry
Indolizidine
Enamine
Chemistry

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