Reactive Cyanine Fluorescence Dyes Indicating pH Perturbation of Biomolecules

E-mail: leekj@hanyang.ac.krReceived September 19, 2012, Accepted October 22, 2012Key Words : Fluorescence dyes, pH Sensitive dyes, Cyanine, Vinylsulfone group, Dye-labeled biomoleculesMaintaining the proper cellular pH is an essential condi-tion for a biological system, and both intra- and extracellularpH levels are influenced by various pathophysiologicalconditions.