Epidemiological evolution of acid peptic disease in an Endoscopic Diagnostic Center in Bogotá from 1993 and 2007

Received: 31-07-09 Accepted: 26-05-10 Abstract Objective: To describe epidemiological characteristics of individuals suffering from acid peptic disease found by a first level endoscopic diagnostic center from 1993 and 2007. Methods: A retrospective, descriptive and analytical study of series of patients. Results: 12,638 registers were included in the study. 62.3% of the patients women, 37.7% were men (mean 44.0 ± 16 years). Main endoscopy findings: peptic esophagitis 14.1%, gastric ulcer 4.1%, duodenal ulcer 7.0%, total acid peptic duodenal lesions 17%. Corporal gastric ulcers were most common (56.4%). Erosive gastric lesions represented 21% of cases. Only the frequency of duodenal acid peptic disease decreased significantly in the period observed. This was associated with increased consumption of proton pump inhibitors. No seasonal variation was observed in any of the lesions. Conclusions: 1. Acid peptic disease is frequently observed at the first level endoscopic center, most frequently in men. 2. We described a significant reduction in the frequency of duodenal acid peptic disease associated with increased consumption of proton pump inhibitors. 3. It is necessary to realize multi-centric studies to confirm our results.