Relationship of plasma lipids and lipoprotein concentration to cerebral atherosclerosis and electrocardiographic findings

Abstract Fasting plasma lipid (cholesterol and triglycerides) and lipoprotein concentrations were measured and 12 lead ECGs performed in 100 consecutive patients (57 males, 43 females) admitted for diagnostic carotid angiography. Their ages ranged from 35 to 64 years with a mean of 51 years. In 40 patients who had evidence of cerebral atherosclerosis, plasma lipid and lipoprotein concentrations were not significantly higher than in those without atheroma. Twenty-three of the 100 subjects had ECG changes indicative of myocardial ischaemia or infarction. In this group the mean plasma cholesterol and low density lipoprotein cholesterol concentrations were significantly ( P