GATA4/FOG2 transcriptional complex regulates Lhx9 gene expression in murine heart development

Background GATA4 and FOG2 proteins are required for normal cardiac development in mice. It has been proposed that GATA4/FOG2 transcription complex exercises its function through gene activation as well as repression; however, targets of GATA4/FOG2 action in the heart remain elusive.