Optical Quantification of Cerebral Hemodynamics During Deep Hypothermic Cardiopulmonary Bypass with Selective Cerebral Perfusion

Non-invasive, frequency-domain diffuse optical spectroscopy and diffuse correlation spectroscopy were combined to quantify cerebral oxygen metabolism in a neonatal swine model of deep hypothermic cardiopulmonary bypass, circulatory arrest, and selective cerebral perfusion.