Zoledronic Acid (Zometa®) Enhances the Cytotoxic Effect of Gemcitabine and Fluvastatin: In vitro Isobologram Studies with Conventional and Nonconventional Cytotoxic Agents

Daniel R. Budman,Anthony Calabro

Zoledronic Acid (Zometa®) Enhances the Cytotoxic Effect of Gemcitabine and Fluvastatin: In vitro Isobologram Studies with Conventional and Nonconventional Cytotoxic Agents

2006

Daniel R. Budman
Anthony Calabro

Objectives: To identify synergistic combinations of clinically available agents with zoledronic acid which would enhance antitumor activity as measured by median effect isobologram

Keywords:

Fluvastatin
Trastuzumab
Zoledronic acid
Pharmacology
Cytotoxicity
Antimetabolite
Gemcitabine
Medicine
MTT assay
Enzyme inhibitor
Cytotoxic T cell
In vitro

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