Ni(II), Pd(II) and Pt(II) complexes with SacNac tridentate ligand

Abstract Organometallic and coordination nickel, palladium and platinum complexes, neutral and cationic, with general formula [M(κ 3 -SacNac)X] and [M(κ 3 -SacNac)L′][BPh 4 ] (where M = Ni, Pd and Pt, X = Me, Cl, 1 – 6 ; M = Ni, X = N 3 , SMe, 7 – 8 ; M = Pd, X = I, 13 ; M = Ni and Pd, L′ = PPh 3 , 9 – 10 ; M = Ni and Pt, X = PMe 3 , dmso, 11 – 12 ) containing a new SacNac N,N,S-tridentate ligand [C 6 H 5 (S)CCH 2 C( N-CH 2 CH 2 NHC 6 H 5 )CH 3 ] were synthetized and obtained as microcrystalline solids. Compounds 2 – 13 were fully characterized by elemental analysis, IR, 1D and 2D NMR spectroscopy. The structure of the ligand and eight complexes was determined by X-ray crystallographic analysis. The ligand can be both mono- or bi-deprotonated under mild reaction conditions. Results in Heck reaction and antiproliferative activities are reported.