Endothelial ALK1 Is a Therapeutic Target to Block Metastatic Dissemination of Breast Cancer

Sara I. Cunha,Matteo Bocci,John Lövrot,Nikolas M. Eleftheriou,Pernilla Roswall,Eugenia Cordero,Linda Sofie Lindström,Michael Bartoschek,B. Kristian Haller,R. Scott Pearsall,Aaron W. Mulivor,Ravindra Kumar,Christer Larsson,Jonas Bergh,Kristian Pietras

Endothelial ALK1 Is a Therapeutic Target to Block Metastatic Dissemination of Breast Cancer

2015

Sara I. Cunha
Matteo Bocci
John Lövrot
Nikolas M. Eleftheriou
Pernilla Roswall
Eugenia Cordero
Linda Sofie Lindström
Michael Bartoschek
B. Kristian Haller
R. Scott Pearsall
Aaron W. Mulivor
Ravindra Kumar
Christer Larsson
Jonas Bergh
Kristian Pietras

These findings offer preclinical proof of concept for the utility of ALK1 inhibitors to treat metastatic breast cancer, with immediate implications for evaluation of this strategy in the clinic.

Keywords:

Breast cancer
Metastatic breast cancer
Medicine
Pathology
Oncology
Internal medicine

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