Catechol- O -methyltransferase (COMT) gene polymorphisms are associated with baseline disability but not long-term treatment outcome in patients with chronic low back pain

Ahmad Omair,Anne F. Mannion,Marit Holden,Jeremy Fairbank,Benedicte A. Lie,Olle Hägg,Peter Fritzell,Jens Ivar Brox

Catechol- O -methyltransferase (COMT) gene polymorphisms are associated with baseline disability but not long-term treatment outcome in patients with chronic low back pain

2015

Ahmad Omair
Anne F. Mannion
Marit Holden
Jeremy Fairbank
Benedicte A. Lie
Olle Hägg
Peter Fritzell
Jens Ivar Brox

Purpose To examine the association between COMT and OPRM1 gene polymorphisms and pain and disability at baseline and long-term follow-up in patients treated for chronic low back pain (LBP).

Keywords:

Physical therapy
Gene
Low back pain
OPRM1 gene
Medicine
Catechol-O-methyl transferase
Single-nucleotide polymorphism
comt gene
chronic low back pain
Neurosurgery
long term treatment
in patient

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