Increased Nuchal Translucency: Is Advanced Sequencing the Answer? A Mini Commentary.

Increased nuchal translucency (NT) on first trimester ultrasound poses a diagnostic and prognostic dilemma. Given association with chromosomal changes and other structural anomalies, an isolated increased NT is an indication to pursue genetic diagnosis. Early diagnosis may aid decisions for pregnancy management as a chromosomal abnormality is identified in 30% of cases.