The Formula of the Waste of Cholesterol a New Way to Increase Over-Life in Patients Affected From Breast Cancer - A Prospective Study

Introduction: Breast cancer represents the first incidence of tumors in the women in occidental countries including Cuba. In this paper we analyze it, taking into account the formula of the waste of cholesterol, and how we can see what we are doing in the adjuvant setting in a prospective and observational study that began in the year 2001. Material and methods: According to the received treatment 365 records of patients with operable breast cancer were reviewed, and relapses before 5 years were analyzed. One group received chemotherapy alone and the other group received chemotherapy +tamoxiefen. The criterion of treatment was based on estrogen receptor status or clinical criteria of hormone dependence. Patients were staged by the TNM classification. Patients' data were collected from the clinical records from the archives of the III Congreso Hospital and were translated to a digital sheet where levels of total cholesterol and HDL cholesterol are introduced, classifying the tumors in high waste of cholesterol or low waste of cholesterol. Results: It was found that the patients with negative waste of cholesterol that received chemotherapy alone had a significant increase of relapses in all stages, including stage I. The results were compared with the paper presented in St Gallen 2001, where the patients did not receive adjuvant therapy. It was seen that when the unbalance of cholesterols increase in patients with negative waste of cholesterol that received adjuvant chemotherapy but did not receive tamoxifen afterwards the percentage of relapses increases. We concluded that adjuvant chemotherapy has to be discussed in patients with negative waste of cholesterol and if it is used it has to be followed by treatment with tamoxifen. for estrogen formation according to age. Normal population has to be in Zero, when the levels of total cholesterol and HDL cholesterol of patients with breast cancer are introduced in the digital sheet the cholesterol waste can be increased or decreased many times, so we can act taking into account what increases or decreases the HDL cholesterol and treat the patient to obtain the normal balance of cholesterols where the immunologic system is competent and apoptosis is available. In that paper it was found that patients of high waste of cholesterol, that are patients with increased relative levels of HDL cholesterol have the most aggressive tumors. In fact it was reported in 2012 by Chritiane Danilo that tumors with higher levels of HDL cholesterol are the most aggressive, which reinforces our results (2). On the other hand the balance of cholesterols where certain cholesterol