The West African Sorghum Bicolor Leaf Sheath Extract Jobelyn® and Its Diverse Therapeutic Potentials

The West African variety of nbsp Sorghum bicolor nbsp leaf sheath SBLS Jobelyn reg nbsp is a natural remedy nbsp which has gained international recognition for its anti anemic effect and energy boosting qualities in debilitating diseases nbsp The widespread use of traditional medicine in the region usually confirms its safety but not its efficacy or deep assessment of their pharmacological properties The other major issue for herbal based treatments is the lack of definite and complete information about the composition of the extracts nbsp nbsp Despite limitations efforts have been made in isolation and characterisation of active compounds in this specie of nbsp sorghum nbsp showing various nbsp subclasses of flavonoids including apigeninidin a stable deoxyanthocyanidin and potential fungal growth inhibitor which accounts for of the total extract nbsp Non clinical in vitro and in vivo studies support previous indications that this variety of nbsp sorghum bicolor nbsp possesses several biologically active compounds with potent antioxidant anti inflammatory anti aging and neuro protective properties nbsp Clinical studies show that nbsp SBLS has the ability nbsp to boost nbsp hemoglobin concentrations in anemic conditions and most remarkably to increase CD count in HIV positive patients The multiple effects and high safety profiles of this extract may encourage its development as a therapeutic agent for the treatment of anemia chronic inflammatory conditions or in the symptomatic management of HIV infections nbsp This review describes nbsp the potential therapeutic aspects nbsp of SBLSextract nbsp and its potential benefits