Global Transcriptomic and Metabolomic Profiling of GPR40 Knock·Out Mouse Islets

1 I Global Transcriptomic and Metabolomic Profiling of GPR40 Knock·Out Mouse Islets. THIERRY A LQUIER'*, MELKAM KEBEDE', STEPHANE GESTA ,CHRISTINA M. SORENSEN' , MARIE·LlNE PEYOT' , RONALD J. MOORE', RONALD C. KAHN , MARC PRENTKJ ', THOMAS O. METZ2, VINCENT POITOUT'. M ontreal Diabetes Research Center, Centre de Recherche du Centre Hospital ier de l 'Universite de Montreal , Montreal, QC, Canada '; Pacific Northwest National Laboratory, Richland, W A, USA 2 ; Joslin Diabetes Center and Harvard Medical School, Boston, MA, USA'