Improved renal function after conversion from tacrolimus/sirolimus to tacrolimus/mycophenolate mofetil in kidney transplant recipients.

Background.There is limited data on the potential nephrotoxicity of sirolimus (SRL) and tacrolimus (TAC) in combination.Methods.We reviewed the course of 97 kidney transplant patients treated with SRL and reduced-dose TAC. Conversion from SRL to mycophenolate mofetil (MMF) was prescribed in a minori