On the integration of ecological and physiological variables in polar bear toxicology research: a systematic review

Ecotoxicology evolved as a scientific field as awareness of the unintended effects of anthropogenic pollutants in biota increased. Polar bears (Ursus maritimus) are often the focus of Arctic contaminant exposure studies because they are apex predators with high contaminant loads. While early studies focused on describing and quantifying pollutants, present-day polar bear toxicological papers often incorporate ecological variables. This systematic literature review investigates the ecological and physiological variables that have been integrated in such studies. The systematic literature search resulted in 207 papers, published 1970-2016. Representation of each of the 19 polar bear subpopulations varied from 0 to 72 papers, with East Greenland, Barents Sea, Southern Beaufort Sea, and Lancaster Sound being the most published with > 30 papers each. Samples were collected between 1881 and 2015, primarily from harvested bears (66%); most from the 1990s and 2000s. Adipose tissue, liver, and blood were the most ...