Modulating cardiac conduction during metabolic ischemia with perfusate sodium and calcium in guinea pig hearts

Sharon A. George,Gregory S. Hoeker,Patrick J. Calhoun,Michael Entz,Tristan Raisch,D. Ryan King,Momina Khan,Chandra Baker,Robert G. Gourdie,James W. Smyth,Morten Schak Nielsen,Steven Poelzing

Modulating cardiac conduction during metabolic ischemia with perfusate sodium and calcium in guinea pig hearts

2019

Sharon A. George
Gregory S. Hoeker
Patrick J. Calhoun
Michael Entz
Tristan Raisch
D. Ryan King
Momina Khan
Chandra Baker
Robert G. Gourdie
James W. Smyth
Morten Schak Nielsen
Steven Poelzing

This study demonstrates, for the first time, that modulating perfusate ion composition can alter cardiac electrophysiology during simulated metabolic ischemia.

Keywords:

Biochemistry
Ischemia
Sodium
Calcium
Cardiac electrophysiology
Guinea pig
Diabetes mellitus
Biology
Pharmacology
cardiac conduction

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