A STUDY ON SOME STRUCTURAL FEATURES RESPONSIBLE FOR SARS-COV-2 INFECTION FATALITY

In this article Covid19 is structurally analysed to establish the pathogenic attack through its spike protein ( 1 ) The most of the bio -macromolecules starting from globular proteins to viruses with a high molecular weight average showing polymeric nature as to induce their biological activities. The tremendous infectivity mainly depends on one most important hydrodynamic properties like Zigzag nature of viral walk ( 2 ) for a specific molecular weight ( M ). Hydrodynamic s nature of mRNA –viruses like SARS-COV-2 is analysed to compute the random– zigzag motion ( 2,3) of the virus known as Radius of Gyration( Rg ) value of virus . For computation of Rg a standard curve( 4 )of Rg – M is statistically analysed with best fit regression analysis like Morgan – Morgan – Finney ( MMF ) ( 5 ) model . This zigzag – random walk ( 2 ) of SARS-COV-2 molecule computed from Rg value may be considered as fatality rate of infection ( 6 ).