Advanced presentation of gallbladder cancer: epidemioclinicopathological study to evaluate the risk factors and assess the outcome.

OBJECTIVE: To evaluate the risk factors and assess the short-term prognosis and independent prognostic factors of cases of gallbladder cancer. METHODS: A retrospective analysis of the data of 52 patients of gallbladder cancer was done. Clinical presentation, laboratory investigations, treatment given, operative findings and histopathological findings were reviewed. RESULTS: Forty-four patients were unresectable at presentation. A 2-year survival rate for early gallbladder cancer was 100% while it was only 29.2% in the advanced stage group. CONCLUSION: The overall 2-year survival rate was 39.58%. The TNM stage was the most important factor affecting the survival.