172 meningiom olgusunun histopatolojik özellikleri

Aim: We aimed to evaluate the incidence and the clinicopathological aspects of meningiomas in our region which had been diagnosed in our laboratory in the last 10 years . Materials and methods: The 172 cases which had been diagnosed as meningioma in Goztepe SSKB Educational Hospital Pathology Laboratory during the period of 19932003 have been reevaluated with respect to their clinical and histopathological features using the 2000 WHO (World Health Organization) classification. Results: Meningiomas comprise the %19,7 of 782 intracranial tumors. 154 of the 172 meningioma cases are located intracranially whereas the 18 are located intraspinally (%10,48). They are frequently located at the parasagital region and at the convexity. Meningioma incidence in females is 2,8 times higher than males. The age range is 2-76, and mean age is 51. %89 of the cases is Grade I, whereas %11 is Grade II. 8 of the cases have recurred. Among these cases only 3 are Grade II. Transitional type (%38,1) is the most common type followed by meningotheliomatous (%23,8), psammomatous (%10,7), atypical (%8,9), fibrous (%8,3), microcystic (%3,6), angiomatous (%2,4), clear cell (%2,4), metaplastic (%1,2) and secretory types (%0,6). Conclusion: Meningiomas are frequently encountered tumors with a wide histological spectrum. Atypia and malignancy criteria have been re-defined and new subtypes have been established. In this respect, the diagnoses are subject to change if the cases are retrospectively analyzed