Population, Epidemiological, and Functional Genetics of Gastric Cancer Candidate Genes in Peruvians with Predominant Amerindian Ancestry

Roxana Zamudio,Latife Pereira,Carolina D. Rocha,Douglas E. Berg,Thaís Muniz-Queiroz,Hanaisa P. Sant Anna,Lilia Cabrera,Juan M. Combe,Phabiola Herrera,Martha H. Jahuira,Felipe B. Leão,Fernanda Lyon,William Prado,Maíra R. Rodrigues,Fernanda Rodrigues-Soares,Meddly L. Santolalla,Camila Zolini,Aristóbolo M. Silva,Robert H. Gilman,Eduardo Tarazona-Santos,Fernanda S. G. Kehdy

Population, Epidemiological, and Functional Genetics of Gastric Cancer Candidate Genes in Peruvians with Predominant Amerindian Ancestry

2016

Background Gastric adenocarcinoma is associated with chronic infection by Helicobacter pylori and with the host inflammatory response triggered by it, with substantial inter-person variation in the immune response profile due to host genetic factors.

Keywords:

Cancer
Candidate gene
Haplotype
Genetic association
Helicobacter pylori
Genetics
Allele frequency
Population
Adenocarcinoma
Biology
chronic infection

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