Histochemical Study of Oxidative Enzymes and Cysteine Desulfurase in Familiar Benign Chronic Pemphigus and Darier's Disease

The activities of oxidative enzymes and cysteine desulfurase were histo-chemically investigated in familiar benign chronic pemphigus and Darier's disease. In the activities of suecinate dehydrogenase and nicotinarnide adenine dinucleotide-dependent dehydrogenases, there was no difference between the two diseases. However, the activity of nicotinamide adenine dinucleotide phos-phate-dependent dehydrogenase showed a remarkable increase in the acantholytic cells in Darier's disease as compared with those in familiar benign chronic pemphigus. A slight activity of cysteine desulfurase was found in the former, but not in the latter.