Anticoagulant effect of dicumarol at various prothrombin levels in dogs.

Conclusions1. The anticoagulant effect of dicumarol at various prothrombin levels in dogs has been studied.2. In control animals thrombosis occurred, on the average, in 6.3 minutes, with a variation from 3 to 10 minutes.3. In dicumarolized dogs the time of thrombosis was not delayed at prothrombin levels above 40%. Below 40% thrombosis occurred on the average, in 16.6 minutes.