A population analysis of nebulized (R)-albuterol in dogs using a novel mixed gut-lung absorption PK-PD model

Purpose. The objectives of this study were to 1) construct a pharmacokinetic-pharmacodynamic (PK-PD) model, and 2) determine the PKs and PDs of (R)-albuterol when given by nebulization to 8 dogs for 7 consecutive days.