Compounds of the cephalosporin and process for their preparation

THE INVENTION CONCERNS A DERIVATIVE CEPHALOSPORIN THIS COMPOUND IS REPRESENTED BY THE GENERAL FORMULA:. (CF DRAWING IN BOPI) WHERE R REPRESENTS A REPRESENTED GROUPS BY THE FORMULA: (CF DRAWING IN BOPI) (R WHERE IS hYDROGEN OR LOWER aLKYL 3ATOMES 1 TO CARBON AND hYDROGEN IS AN R, I RENT A LOWER 1 TO CARBON 3ATOMES , A pHENYL WHICH CAN BE sUBSTITUTED AMINO OR hYDROXY, A cYANO, A cARBOXY or carboxymethyl; SUCH R AND R CAN FORM cycloalkylidene GROUP 4 A 6ATOMES CARBON SET WITH CARBON ON WHICH THEY ARE LINKED) OR GROUP REPRESENTED BY THE FORMULA CH-R (R IN WHICH REPRESENTS A hYDROGEN, halomethyl, cARBAMOYL, carboxymethyl, cARBOXY-4-HYDROXY-3-isothiazolyl-5-thiomethyl OR carboxyphenyl-2-thiomethyl); R REPRESENTS THE REPRESENTED GROUPS BY THE FORMULA: (CF DRAWING IN BOPI) (WHERE R REPRESENTS A CARBOXY, A CYANO CARBAMOYL OR WHICH CAN BE REPLACED BY 1 TO LOWER ALKYL 3ATOMES CARBON R AND REPRESENTS A hYDROXY AMINO OR) OR REPRESENTED GROUPS BY THE FORMULA: (CF DRAWING IN BOPI) (IN WHICH R AND R HAVE THE SAME MEANING AS ABOVE); WAVE AND REPRESENTS OR LINK CIS SYN AND THEIR SALTS. THE COMPOUND IS EFFECTIVE AGAINST GRAM-NEGATIVE BACTERIA AND BACTERIA GRAM-POSITIVE.