Determination of 43 pesticide residues in grape wine by solid-phase dispersion and gas chromatography-mass spectrometry.

Objective A rapid analytical method was developed for the determination of 43 pesticide residues in grape wine by solid-phase dispersion with gas chromatography-mass spectrometry(GC/MS).Methods Toally 43 pesticide residues were extracted from the samples with acetonitrile,and then detected by GC/MS with external standard method after being cleaned up with three sorbents(PSA 80.0 mg、GCB 30.0 mg and NH_2 30.0 mg).Results Good linearities of 10~500 μg/L were obtained and correlation coefficients were0.9851~0.9997.The recoveries of all pesticides were in the range from 67.43% to 114.74% at the spiked levels of 50,100,and 200 μg/kg in grape wine,and the relative standard deviations(RSDs)were not more than 13.6%.The limits of detection(LOD)were 1~50 μg/kg.Conclusion The method could be used for the determination of 43 pesticide residues in grape wine due to its simpleness,accuracy and rapidness.