Prognostic impact of platelet-derived growth factor in breast carcinoma patients with hematogenous metastasis

Background. Many recent studies have found that several angiogenic factors play an important role in primary and metastatic tumor growth. Platelet-derived growth factor (PDGF) is known to induce angiogenesis. In this study, we investigated whether tumor PDGF can reliably predict metastatic potential and survival benefit in patients with breast cancer.