Lipoprotein lipase and metabolic syndrome

Lipoprotein lipase (LPL) is the key enzyme in metabolism of lipids,which mainly hydrolyzes triglyceride (TG) and plays an important role in the metabolism of chylomicrons (CM)and very low density lipoprotein(VLDL).The defect of LPL or its abnormal activity can induce dyslipidemia and glucose metabolism disorder.Metabolic syndrome (MS) is a clinical syndrome which characterized by the cluster of cardiovascular risk factors,such as abdominal obesity,hypertension and glycolipids metabolism disorders.LPL is now considered to play an important role in the occurrence and development of MS by more and more animal and cilinical evidences,and the research of LPL will help to explore new therapeutic direction for MS. Key words: Lipoprotein lipase ;  Metabolic syndrome ;  Lipid metabolism ;