Treatment during a vulnerable developmental period rescues a genetic epilepsy

Stephan Lawrence Marguet,Vu Thao Quyen Le-Schulte,Andrea Merseburg,Axel Neu,Ronny Eichler,Igor Jakovcevski,Anton Ivanov,Ileana L. Hanganu-Opatz,Christophe Bernard,Fabio Morellini,Dirk Isbrandt

Treatment during a vulnerable developmental period rescues a genetic epilepsy

2015

Stephan Lawrence Marguet
Vu Thao Quyen Le-Schulte
Andrea Merseburg
Axel Neu
Ronny Eichler
Igor Jakovcevski
Anton Ivanov
Ileana L. Hanganu-Opatz
Christophe Bernard
Fabio Morellini
Dirk Isbrandt

Treatment with the common diuretic bumetanide during a susceptible developmental window prevents epileptogenesis in a mouse model of a genetic epileptic encephalopathy.

Keywords:

KCNQ Potassium Channels
Epilepsy
Immunology
Epileptic encephalopathy
Proto-Oncogene Proteins c-fos
Body weight
Bumetanide
Medicine
Epileptogenesis
Endocrinology
Internal medicine
Bioinformatics
Mutation
preclinical research
genetic epilepsy

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