Low-dose and high-dose adrenocorticotropin testing: indications and shortcomings

Purpose of reviewThe 250 μg adrenocorticotropin test (high-dose test) is the most commonly used adrenal stimulation test, though the use of physiologic doses (1.0 μg or 0.5 μg/1.73 m2) (low-dose test) has recently gained wider acceptance. These variants and the use of adrenocorticotropin test in the