Assessing responsiveness over time of the PROMIS ® pediatric symptom and function measures in cancer, nephrotic syndrome, and sickle cell disease

Purpose Previous studies provided evidence for the validity of the PROMIS Pediatric measures in cross-sectional studies. This study evaluated the ability of the PROMIS Pediatric measures to detect change over time in children and adolescents with cancer, nephrotic syndrome (NS), or sickle cell disease (SCD).