Diagnostic Yield of Saliva for SARS-CoV-2 Molecular Testing in Children.

Dithi Banerjee,Anjana Sasidharan,Ayah Abdulhamid,Esmeralda M Orosco,Jennifer L Watts,Jennifer E. Schuster,Angela L. Myers,Gina Weddle,Rangaraj Selvarangan

Diagnostic Yield of Saliva for SARS-CoV-2 Molecular Testing in Children.

2021

Dithi Banerjee
Anjana Sasidharan
Ayah Abdulhamid
Esmeralda M Orosco
Jennifer L Watts
Jennifer E. Schuster
Angela L. Myers
Gina Weddle
Rangaraj Selvarangan

Pediatric saliva specimen demonstrated high sensitivity (93%) and specificity (96.2%) compared to paired nasopharyngeal swabs (NPS) by Aptima SARS-CoV-2 Assay (Aptima). Viral loads were comparable in both specimen types. Saliva is a safe, noninvasive, and acceptable alternative specimen for SARS-CoV-2 detection in children.

Keywords:

severe acute respiratory syndrome coronavirus 2
Gastroenterology
Coronavirus disease 2019
Saliva specimen
Saliva
Internal medicine
Viral load
2019 20 coronavirus outbreak
Medicine

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