MGMT (06-methylguanine-DNA methyltransferase) promoter hypermethylation in the context of colorectal cancer.

Elisabeth Luporsi-Gely,Amandine Cadènes,Myriam Bronner,Hélène de Romémont,Dominique Saint Dizier,Ludovic Mansuy,Pierre Lehair,Philippe Jonveaux

MGMT (06-methylguanine-DNA methyltransferase) promoter hypermethylation in the context of colorectal cancer.

2015

Elisabeth Luporsi-Gely
Amandine Cadènes
Myriam Bronner
Hélène de Romémont
Dominique Saint Dizier
Ludovic Mansuy
Pierre Lehair
Philippe Jonveaux

e14654 Background: This study reports an incidental finding we observed by studying MLH1 promoter methylation in patients (pts) suspected with Lynch Syndrome by MS-MLPA. In 58% of the cases, MGMT p...

Keywords:

Pathology
Cancer research
DNA methylation
Colorectal cancer
Methylguanine-DNA Methyltransferase
Medicine
MLH1
promoter methylation
promoter hypermethylation
Lynch syndrome
in patient

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