Response: antiapoptotic function of Toso (Faim3) in death receptor signaling

We appreciate the interest in our work. In their comment Honjo et al argue that Toso per se would not have antiapoptotic activity on CD95-induced apoptosis,[1][1] as, in contrast to our findings,[2][2] inhibitory activity would only be observed upon on CD95-ligation by the IgM mAb CH11. Our