Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.

Eva Ellinghaus,David Ellinghaus,Philip E. Stuart,Rajan P. Nair,Sophie Debrus,John V. Raelson,Majid Belouchi,Hélène Fournier,Claudia Reinhard,Jun Ding,Yun Li,Trilokraj Tejasvi,Johann E. Gudjonsson,Stefan W. Stoll,John J. Voorhees,Sylviane Lambert,Stephan Weidinger,Bernadette Eberlein,Manfred Kunz,Proton Rahman,Dafna D. Gladman,Christian Gieger,H.-Erich Wichmann,Tom H. Karlsen,Gabriele Mayr,Mario Albrecht,Dieter Kabelitz,Ulrich Mrowietz,Gonçalo R. Abecasis,James T. Elder,Stefan Schreiber,Michael Weichenthal,Andre Franke

Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.

2010

Psoriasis is a multifactorial skin disease characterized by epidermal hyperproliferation and chronic inflammation, the most common form of which is psoriasis vulgaris (PsV). We present a genome-wide association analysis of 2,339,118 SNPs in 472 PsV cases and 1,146 controls from Germany,

Keywords:

Psoriasis
Genetic association
Arthritis
Locus (genetics)
Genetics
Disease
Immunology
Single-nucleotide polymorphism
Genotype
Genome-wide association study
Biology
Gene
Cohort
German

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