The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial.

Vasilios Zachariadis,Fredrika Gauffin,Ekaterina Kuchinskaya,Melvin B. Heyman,Jacqueline Schoumans,Elisabeth Blennow,Britt Gustafsson,Gisela Barbany,Irina Golovleva,Hans Ehrencrona,Lucia Cavelier,Linda Palmqvist,Gudmar Lönnerholm,Magnus Nordenskjöld,Bertil Johansson,Erik Forestier,Agneta Nordgren

The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial.

2011

Vasilios Zachariadis
Fredrika Gauffin
Ekaterina Kuchinskaya
Melvin B. Heyman
Jacqueline Schoumans
Elisabeth Blennow
Britt Gustafsson
Gisela Barbany
Irina Golovleva
Hans Ehrencrona
Lucia Cavelier
Linda Palmqvist
Gudmar Lönnerholm
Magnus Nordenskjöld
Bertil Johansson
Erik Forestier
Agneta Nordgren

The dic(9;20)(p13.2;q11.2) is reported to be present in ∼2% of childhood B-cell precursor acute lymphoblastic leukemia (BCP ALL). However, it easily escapes detection by G-banding analysis and its ...

Keywords:

Dicentric chromosome
Clinical trial
Cancer
Genetics
Cancer research
Hematology
Lymphoblastic Leukemia
Cytogenetics
Biology
B cell
Internal medicine
CDKN2A
Hyperdiploidy
Fluorescence in situ hybridization

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