Direct and Rapid Multi-Element Analysis of Wine Samples in Their Natural Liquid State by Laser Ablation ICPMS

This paper proposes firstly using laser ablation inductively coupled plasma mass spectrometry (LA-ICPMS) for direct multi-element analysis of wine samples without any pretreatment process. As a micro-sample consumption system, this method not only avoids the risk of clogging by carbon deposits but also greatly reduces the matrix effects based on the indifference of the analytical results to the variation in the ethanol concentration (1%–20%) and better analytical performance for undiluted samples with a high salt content. With indium as the internal standard, either the solid reference material NIST 610 glass or aqueous standard solution can be adopted as the external calibration standard; this offers a solution to the lack of a multi-element certified wine reference material for matrix-matched calibration on the market. Twenty elements (Li, B, Mg, Al, V, Mn, Co, Cu, Zn, Rb, Sr, Y, Cs, Ba, La, Ce, Pr, Nd, Pb, and U) were determined in wine samples, and the proposed method was validated by a comparison with the results obtained by conventional solution nebulization ICPMS. The detection limits for these elements were 0.01–1 ng mL-1. This is a simple and rapid method for effective and accurate multi-element analysis of wine and can potentially be applied to other beverages.